Expression genomics in breast cancer research: microarrays at the crossroads of biology and medicine

@article{Miller2007ExpressionGI,
  title={Expression genomics in breast cancer research: microarrays at the crossroads of biology and medicine},
  author={Lance D. Miller and Edison T. Liu},
  journal={Breast Cancer Research},
  year={2007},
  volume={9},
  pages={206 - 206}
}

• Lance D. Miller, Edison T. Liu
• Published 2007 in Breast Cancer Research
• DOI:10.1186/bcr1662

Genome-wide expression microarray studies have revealed that the biological and clinical heterogeneity of breast cancer can be partly explained by information embedded within a complex but ordered transcriptional architecture. Comprising this architecture are gene expression networks, or signatures, reflecting biochemical and behavioral properties of tumors that might be harnessed to improve disease subtyping, patient prognosis and prediction of therapeutic response. Emerging 'hypothesis-driven… CONTINUE READING

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