Expression evolution in yeast genes of single-input modules is mainly due to changes in trans-acting factors.

@article{Wang2007ExpressionEI,
  title={Expression evolution in yeast genes of single-input modules is mainly due to changes in trans-acting factors.},
  author={Daryi Wang and Huang-Mo Sung and Tzi-Yuan Wang and Chih-Jen Huang and Peggy H. Yang and Tiffany P. Chang and Y Ken Wang and Da-Lun Tseng and Jen-Pey Wu and Tso-Ching Lee and Ming-Che Shih and Wen-Hsiung Li},
  journal={Genome research},
  year={2007},
  volume={17 8},
  pages={
          1161-9
        }
}
Both cis- and trans-regulatory mutations contribute to gene expression divergence within and between species. To estimate their relative contributions, we examined two yeast strains, BY (a laboratory strain) and RM (a wild strain), for their gene-expression divergence by microarray. Using these data and published ChIP-chip data, we obtained a set of single-regulator-regulated genes that showed expression divergence between BY and RM. We randomly selected 50 of these genes for further study. We… CONTINUE READING

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