Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum.

@article{Bellmann2001ExpressionCA,
  title={Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum.},
  author={Astrid Bellmann and M Vrlji{\'c} and Miroslav P{\'a}tek and Hermann 4 Sahm and R. Andreas Kraemer and Lothar Eggeling},
  journal={Microbiology},
  year={2001},
  volume={147 Pt 7},
  pages={1765-74}
}
LysE of Corynebacterium glutamicum belongs to a large new superfamily of translocators whose members are probably all involved in the export of small solutes. Here, the transcript initiation site of lysE, and its divergently transcribed regulator gene, lysG, are identified. Single-copy transcriptional fusions of lysE with lacZ, and titration experiments, show that LysG is the positive regulator of lysE expression enabling its up to 20-fold induction. This induction requires the presence of a… CONTINUE READING
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