Expression cloning of new receptors used by simian and human immunodeficiency viruses.

Abstract

Several members of the chemokine-receptor family serve, in conjunction with CD4, as receptors for the entry of human immunodeficiency virus type I (HIV-1) into cells. The principal receptor for entry of macrophage-tropic (M-tropic) HIV-1 strains is CCR5, whereas that for T-cell-line-tropic (T-tropic) strains is CXCR4. Unlike HIV-1, infection with either M… (More)

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@article{Deng1997ExpressionCO, title={Expression cloning of new receptors used by simian and human immunodeficiency viruses.}, author={Hon Kuan Deng and Derya Unutmaz and Vineet N Kewalramani and Dan R. Littman}, journal={Nature}, year={1997}, volume={388 6639}, pages={296-300} }