Expression and significance of miR-21 in multiple myeloma patients.

  title={Expression and significance of miR-21 in multiple myeloma patients.},
  author={J H Wang and W W Zhou and B. X. Liu and Dongliang Man and Z. -D. Yang and F R Liu and Hong Shang},
  journal={Genetics and molecular research : GMR},
  volume={15 1}
The aim of the present study is to examine the expression level of peripheral mir-21 in multiple myeloma (MM) patients and to determine its clinical significance. MM patients (30), monoclonal gammopathy of undetermined significance (MGUS) patients (14), and normal controls (20) were recruited to determine the serum level of β2-MG, IgA and IgM, IgG, λ, κ, TP, ALB, Hb, LDH, and Ca(2+). Gene expression of mir-21 was quantified by SYBR green real-time fluorescent quantitative PCR. We found that the… 

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