Expression and significance of hypoxia-inducible factor-1α and glucose transporter-1 in laryngeal carcinoma.

@article{Wu2013ExpressionAS,
  title={Expression and significance of hypoxia-inducible factor-1α and glucose transporter-1 in laryngeal carcinoma.},
  author={Xiao-hong Wu and Su-Ping Chen and Jian-Ying Mao and Xue-Xian Ji and Hong-tian Yao and Shui-Hong Zhou},
  journal={Oncology letters},
  year={2013},
  volume={5 1},
  pages={261-266}
}
Malignant cells show increased glucose uptake in vitro and in vivo. This process is considered to be mediated by glucose transporters (GLUTs). Hypoxia-inducible factor-1α (HIF-1α) may upregulate GLUT-1 expression. Little is known about the correlation between HIF-1α and GLUT-1 expression in laryngeal carcinoma. The current study investigated this correlation immunohistochemically, according to various clinical and pathological features, in 49 paraffin-embedded archival tissue blocks from… CONTINUE READING
Highly Cited
This paper has 29 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…