Expression and role of the cell surface protease seprase/fibroblast activation protein-α (FAP-α) in astroglial tumors.


Seprase or fibroblast activation protein-α (FAP-α) is a cell-surface serine protease that was previously described nearly exclusively on reactive and tumor stromal fibroblasts and thought to be involved in tissue remodeling. We investigated the expression and significance of FAP-α in astrocytomas/glioblastomas. As shown by quantitative reverse transcription… (More)
DOI: 10.1515/BC.2010.119


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