Expression and role of laminin-1 in mouse pancreatic organogenesis.

@article{Crisera2000ExpressionAR,
  title={Expression and role of laminin-1 in mouse pancreatic organogenesis.},
  author={Christopher A. Crisera and Alan S. Kadison and Gary D Breslow and Thomas Maldonado and Michael Thornton Longaker and George K. Gittes},
  journal={Diabetes},
  year={2000},
  volume={49 6},
  pages={936-44}
}
Previous studies have suggested that basement membrane alone may induce ductal differentiation and morphogenesis in the undifferentiated embryonic pancreas. The mechanism by which this induction occurs has not been investigated. Studies of other organ systems such as the lungs and mammary glands, where differentiation has been shown to be induced by basement membrane, have suggested a major role for laminin as a mediator of ductal or tubular morphogenesis and differentiation. We first defined… CONTINUE READING

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