Expression and role of c-myc in chondrocytes undergoing endochondral ossification.

  title={Expression and role of c-myc in chondrocytes undergoing endochondral ossification.},
  author={Masahiro Iwamoto and Kimitosi Yagami and P Lu Valle and Bjorn Reino Olsen and Christos J. Petropoulos and Donald L. Ewert and Maurizio Pacifici},
  journal={The Journal of biological chemistry},
  volume={268 13},
To analyze the relationship between c-myc gene expression and chondrocyte proliferation and maturation during endochondral ossification, Day 18-19 chick embryo sterna were pulse-labeled with [3H]thymidine, and serial sections were processed for autoradiography and in situ hybridization. Proliferating chondrocytes, located in four distinct areas of the developing sternum, all contained high levels of c-myc transcripts, whereas postmitotic chondrocytes (such as hypertrophic chondrocytes… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 13 extracted citations

c-Myc overexpression increases cell size and impairs cartilage differentiation during chick limb development.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research • 2002


Publications referenced by this paper.
Showing 1-3 of 3 references

A c d Scl

N Y.
View 1 Excerpt
Highly Influenced

Methods Enzymol

J. T. Lis
J. Biol. Chem • 1989
View 1 Excerpt
Highly Influenced

Cytometry 9

R. Cancedda
Proc. Natl. Acad. Sci • 1988

Similar Papers

Loading similar papers…