Expression and role of PDGF-BB and PDGFR-beta during testis morphogenesis in the mouse embryo.

@article{Puglianiello2004ExpressionAR,
  title={Expression and role of PDGF-BB and PDGFR-beta during testis morphogenesis in the mouse embryo.},
  author={Antonella Puglianiello and Luisa Campagnolo and Donatella Farini and Daria Cipollone and Mario Antonio Russo and Gregorio Siracusa},
  journal={Journal of cell science},
  year={2004},
  volume={117 Pt 7},
  pages={1151-60}
}
The role played by PDGF in testis morphogenesis is still incompletely understood. The present study investigates the expression and potential role of platelet-derived growth factor-BB (PDGF-BB) and its receptor, PDGF receptor beta (PDGFR-beta), during mouse testis cord formation, and the possibility that the growth factor may be involved in the migration to the gonad of mesenchymal cells of mesonephric origin. Studies from this laboratory have previously shown that mesenchymal cells that… CONTINUE READING

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