Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29.

  title={Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29.},
  author={Shaoheng He and Huihao Zhang and H Chen and Hongbin Yang and Tsun-Tsao Huang and Yuan Chen and Jian'an Lin and Fengying Wang and Xuru Chen and Tian Li and Ping-Chang Yang},
  volume={65 10},
BACKGROUND The role of interleukin (IL)-29 in innate immunity has been recognized recently, and it is regarded as a potent bioactive molecule. However, little is known about its role in the pathogenesis of allergy. Because mast cells are recognized as primary effector cells of allergy, we investigated the potential relationship between IL-29 and mast cells in this study. OBJECTIVE To examine the expression of IL-29 in mast cells and the influence of IL-29 on mast cell mediator release and… CONTINUE READING


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