Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta.

@article{Holmlund2002ExpressionAR,
  title={Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta.},
  author={Ulrika Holmlund and Gvido Cebers and Agneta R Dahlfors and Bengt Sandstedt and Katarina A Bremme and E Sverremark Ekstr{\"o}m and A Scheynius},
  journal={Immunology},
  year={2002},
  volume={107 1},
  pages={145-51}
}
The placenta constitutes a physical and immunological barrier against invading infectious agents and has been suggested to be a pregnancy-specific component of the innate immune system. The aim of this study was to investigate the presence and regulation of Toll-like receptors-2 and -4 (TLR2 and TLR4) in the human placenta, because these receptors are believed to be important for immune responses against pathogens. Twenty-eight placentas from normal term pregnancies were analysed with… CONTINUE READING