Expression and regulation of long noncoding RNAs in TLR4 signaling in mouse macrophages

@inproceedings{Mao2015ExpressionAR,
  title={Expression and regulation of long noncoding RNAs in TLR4 signaling in mouse macrophages},
  author={Ai-Ping Mao and Jun Shen and Zhixiang Zuo},
  booktitle={BMC Genomics},
  year={2015}
}
Though long non-coding RNAs (lncRNAs) are emerging as critical regulators of immune responses, whether they are involved in LPS-activated TLR4 signaling pathway and how is their expression regulated in mouse macrophages are still unexplored. By repurposing expression microarray probes, we identified 994 lncRNAs in bone marrow-derived macrophages (BMDMs) and classified them to enhancer-like lncRNAs (elncRNAs) and promoter-associated lncRNAs (plncRNAs) according to chromatin signatures defined by… CONTINUE READING