Expression and regulation of golli products of myelin basic protein gene during in vitro development of oligodendrocytes.

@article{Givogri2001ExpressionAR,
  title={Expression and regulation of golli products of myelin basic protein gene during in vitro development of oligodendrocytes.},
  author={Maria Irene Givogri and Ernesto R Bongarzone and Vilma Schonmann and Anthony T. Campagnoni},
  journal={Journal of neuroscience research},
  year={2001},
  volume={66 4},
  pages={679-90}
}
The myelin basic protein (MBP) gene produces two families of proteins, the classic MBPs, important for myelination of the CNS, and the golli proteins, whose biological role in oligodendrocytes (OLs) is still unknown. The goals of this work were to study the in vitro pattern of expression of the golli products during OL differentiation and to compare it with that of the classic MBP products of the gene. Mouse primary glial cultures were analyzed at the mRNA and protein levels with an array of… CONTINUE READING