Expression and regulation of chemokine genes in the mouse uterus during pregnancy.

@article{Wood1999ExpressionAR,
  title={Expression and regulation of chemokine genes in the mouse uterus during pregnancy.},
  author={Gary W. Wood and E H Hausmann and K Kanakaraj},
  journal={Cytokine},
  year={1999},
  volume={11 12},
  pages={1038-45}
}
Leukocytes accumulate in the pregnant mouse uterus following mating, during implantation and during placental development. Changes in leukocyte number are primarily due to recruitment from the blood, not local proliferation, but the underlying recruitment mechanisms are poorly understood. Mating-induced granulocyte and macrophage recruitment is due in part to pro-inflammatory and chemotactic factors present in seminal plasma. Accumulation of macrophages later in pregnancy appears to be caused… CONTINUE READING