Expression and regulation of CCL15 by human airway smooth muscle cells.

  title={Expression and regulation of CCL15 by human airway smooth muscle cells.},
  author={Pierre Joubert and St{\'e}phane Lajoie-Kadoch and Vincent Wellemans and S{\'e}verine L{\'e}tuv{\'e} and Meri Katarina Tulic and Andrew J Halayko and Qutayaba Hamid},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  volume={42 1},
BACKGROUND Structural cells are an important reservoir of chemokines that coordinate the influx of various immune cells to the lungs of asthmatics. Airway smooth muscle cells (ASMC) are an important source of these chemokines. CCL15 is a recently described chemo-attractant for neutrophils, eosinophils, monocytes and lymphocytes. OBJECTIVE To determine the production and the regulation of CCL15 by ASMC and to investigate its production in asthmatic airways. METHODS Human ASMC were obtained… CONTINUE READING
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