Expression and regulation of C/EBPα in normal myelopoiesis and in malignant transformation.


One of the most studied transcription factors in hematopoiesis is the leucine zipper CCAAT-enhancer binding protein α (C/EBPα), which is mainly involved in cell fate decisions for myeloid differentiation. Its involvement in acute myeloid leukemia (AML) is diverse, with patients frequently exhibiting mutations, deregulation of gene expression, or alterations… (More)
DOI: 10.1182/blood-2016-09-687822


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