Expression and reconstitution of the gH/gL/gO complex of human cytomegalovirus.


BACKGROUND All herpesviruses examined to date encode a heterodimeric envelope complex consisting of glycoprotein H (gH) and glycoprotein L (gL); however, co-expression of human cytomegalovirus (HCMV) gH and gL is not sufficient to reconstitute the high molecular weight complex seen in infected cells. Previously, we showed that HCMV encodes a third… (More)


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