Expression and purification of recombinant antigens of Mycobacterium tuberculosis for application in serodiagnosis.

@article{Kulshrestha2005ExpressionAP,
  title={Expression and purification of recombinant antigens of Mycobacterium tuberculosis for application in serodiagnosis.},
  author={Abhishek Kulshrestha and Amita Jain Gupta and Nitin Verma and Shiv Kumar Sharma and Anil K Tyagi and Vijay K Chaudhary},
  journal={Protein expression and purification},
  year={2005},
  volume={44 1},
  pages={75-85}
}
Accurate diagnosis is essential for the treatment, prevention, and control of tuberculosis. Poor specificity of the tuberculin skin test in BCG-vaccinated populations and constraints to implementation of PCR and CMI-based diagnostic assays in developing countries warrant development of easy-to perform robust serological tests. Due to great heterogeneity in humoral response in TB patients, it will be necessary to include several antigens in any diagnostic assay to achieve useful levels of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…