Expression and purification of biologically active human OSF-1 in Escherichia coli.

@article{Takamatsu1992ExpressionAP,
  title={Expression and purification of biologically active human OSF-1 in Escherichia coli.},
  author={Haru Takamatsu and Masayuki Itoh and Masato Kimura and Denis Gospodarowicz and Egon P. Amann},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={185 1},
  pages={224-30}
}
OSF-1 (also known as pleiotrophin, HB-GAM, HBGF-8 or HBNF) is a heparin-binding, neurotrophic protein. Its tissue-specific expression in rats is developmentally regulated and the protein is highly conserved between species. The protein is believed to be involved in neuronal development. Previous experiments in our laboratory showed that OSF-1 is primarily… CONTINUE READING