Corpus ID: 19818758

Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor.

@article{FaureHalley1993ExpressionAP,
  title={Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor.},
  author={C. Faure-Halley and D. Graham and S. Arbilla and S. Langer},
  journal={European journal of pharmacology},
  year={1993},
  volume={246 3},
  pages={
          283-7
        }
}
  • C. Faure-Halley, D. Graham, +1 author S. Langer
  • Published 1993
  • Medicine
  • European journal of pharmacology
  • The interaction of omega (benzodiazepine) modulatory drugs with transiently expressed alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor was investigated using [3H]flumazenil as a probe in in vitro radioligand binding assays. The imidazopyridines alpidem and zolpidem exhibited pronounced selectivity for the alpha 1- compared to the alpha 5-containing construct, whereas omega (benzodiazepine) site modulatory compounds from other chemical series including diazepam… CONTINUE READING
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