Expression and prognostic value of tumor stem cell markers ALDH1 and CD133 in colorectal carcinoma

  title={Expression and prognostic value of tumor stem cell markers ALDH1 and CD133 in colorectal carcinoma},
  author={Fei Zhou and Yin-Dong Mu and Jun Liang and Zhi-xin Liu and Hongsheng Chen and Ji-Fei Zhang},
  booktitle={Oncology letters},
The identification of cancer stem cells (CSCs) has improved the understanding of tumor occurrence and development. According to CSC theory, colorectal carcinoma (CRC) may be derived from these few cells. Thus, markers for CSCs may lead to the identification of CSCs and investigation of the correlation with various clinicopathological features and survival time in human CRC patients. Aldehyde dehydrogenase 1 (ALDH1) and CD133 (also known as Prominin-1 or AC133) were involved in the current study… CONTINUE READING


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