Expression and prognostic significance of Stat5a and E-cadherin in extramammary Paget's disease.

@article{Liu2007ExpressionAP,
  title={Expression and prognostic significance of Stat5a and E-cadherin in extramammary Paget's disease.},
  author={Houjun Liu and Kazunori Urabe and Hiroshi Uchi and Satoshi Takeuchi and T Nakahara and Teruki Dainichi and Yating Tu and Masutaka Furue and Yoichi Moroi},
  journal={Journal of cutaneous pathology},
  year={2007},
  volume={34 1},
  pages={33-8}
}
BACKGROUND Stat5 has been shown to regulate the proliferation and inhibition of apoptosis in cancer cells. E-cadherin plays an important role in maintaining epithelial stability and is widely regarded as a prognostic marker in many types of human cancers. The expression of Stat5 has not been investigated in extramammary Paget's disease (EMPD). OBJECTIVES To study the expression of Stat5a and E-cadherin protein in EMPD and to evaluate the relationships between them. METHODS Thirty-six tissue… CONTINUE READING