Expression and possible function of fibroblast growth factor 9 (FGF9) and its cognate receptors FGFR2 and FGFR3 in postnatal and adult retina.

@article{Cinaroglu2005ExpressionAP,
  title={Expression and possible function of fibroblast growth factor 9 (FGF9) and its cognate receptors FGFR2 and FGFR3 in postnatal and adult retina.},
  author={Ayca Cinaroglu and Yesim Ozmen and Anil Ozdemir and Ferruh Ozcan and Ceren Ergorul and Pelin Cayirlioglu and David W. Hicks and Kuyas Bugra},
  journal={Journal of neuroscience research},
  year={2005},
  volume={79 3},
  pages={329-39}
}
Fibroblast growth factors (FGFs) are important regulators of retinal development and survival. We examined the expression and distribution of FGF9 and its preferred receptors FGFR2IIIc and FGFR3IIIc in this tissue. FGF9 transcripts in whole rat retina were detected by RT-PCR but were not present in purified cultured Muller glia. Transcripts appeared as 3.2-kb and 4.0-kb bands on Northern blots, and Western blotting of whole retina revealed FGF9-immunoreactive bands at 30 and 55 kDa. FGF9 mRNA… CONTINUE READING

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