Expression and pharmacological modulation of visceral pain-induced conditioned place aversion in mice

@article{Bada2016ExpressionAP,
  title={Expression and pharmacological modulation of visceral pain-induced conditioned place aversion in mice},
  author={Deniz Bağdaş and Pretal P. Muldoon and Shakir D. Alsharari and F Ivy Carroll and Mohamad Imad Damaj},
  journal={Neuropharmacology},
  year={2016},
  volume={102},
  pages={236-243}
}
Pain encompasses both a sensory as well as an affective dimension and these are differentially processed in the brain and periphery. It is therefore important to develop animal models to reflect the non-reflexive assays in pain. In this study, we compared effects of the mu opioid receptor agonist morphine, the nonsteroidal anti-inflammatory drug ketoprofen and the kappa receptor opioid agonist U50,488H and antagonist JDTic on acetic acid-induced stretching and acetic acid-induced aversion in… CONTINUE READING