Expression and mutation pattern of β-catenin and adenomatous polyposis coli in colorectal cancer patients.

Abstract

BACKGROUND AND AIMS β-Catenin and adenomatous polyposis coli (APC) are major components of the Wnt pathway. This study aimed to investigate the expression of β-catenin and APC in tumors and lymph nodes in colorectal cancer (CRC) patients and the mutational spectrum of the genes coding these proteins. METHODS Expression of APC and β-catenin was examined in… (More)
DOI: 10.1016/j.arcmed.2015.01.001

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