Expression and localization of a UT-B urea transporter in the human bladder.

@article{Walpole2014ExpressionAL,
  title={Expression and localization of a UT-B urea transporter in the human bladder.},
  author={Caragh Walpole and Amy Farrell and Alison McGrane and Gavin S. Stewart},
  journal={American journal of physiology. Renal physiology},
  year={2014},
  volume={307 9},
  pages={F1088-94}
}
Facilitative UT-B urea transporters have been shown to play an important role in the urinary concentrating mechanism. Recent studies have now suggested a link between UT-B allelic variation and human bladder cancer risk. UT-B1 protein has been previously identified in the bladder of various mammalian species, but not yet in humans. The aim of the present study was to investigate whether any UT-B protein was present in the human bladder. First, RT-PCR results confirmed that UT-B1 was strongly… CONTINUE READING
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