Expression and localization of Fas-associated proteins following focal cerebral ischemia in rats

@article{Bi2008ExpressionAL,
  title={Expression and localization of Fas-associated proteins following focal cerebral ischemia in rats},
  author={Fang-fang Bi and Bo Xiao and Yue-qiang Hu and Fa-fa Tian and Xin-fu Zhou},
  journal={Brain Research},
  year={2008},
  volume={1191},
  pages={30-38}
}
The aim of this study was to investigate the changes of expression of Fas-associated proteins and its cellular localization in the peri-infarct region following transient focal cerebral ischemia. Adult male Sprague-Dawley rats underwent right middle cerebral artery occlusion (MCAo) for 2 h and reperfusion for 1, 3, 6, 12 and 24 h. The expression of Fas-associated death domain protein (FADD), Fas-associated phosphatase-1 (FAP-1) caspase-8 and death-associated protein (Daxx), the pro-apoptotic… CONTINUE READING

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