Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues.

@article{SchltzerSchrehardt2002ExpressionAL,
  title={Expression and localization of FP and EP prostanoid receptor subtypes in human ocular tissues.},
  author={Ursula M. Schl{\"o}tzer-Schrehardt and Matthias Zenkel and Rolf Michael N{\"u}sing},
  journal={Investigative ophthalmology & visual science},
  year={2002},
  volume={43 5},
  pages={1475-87}
}
PURPOSE To determine the expression and precise cellular and subcellular localization of the EP prostanoid receptor subtypes EP(1) through EP(4) and the FP receptor in normal human ocular tissues on the protein and mRNA levels. METHODS Expression of EP and FP receptor proteins was examined by immunohistochemistry on the light microscopic level, using subtype-specific antibodies on frozen and paraffin-embedded tissue sections of 10 normal human donor eyes. The subcellular distribution of the… CONTINUE READING

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