Expression and localization of ATP binding cassette transporter A1 (ABCA1) in first trimester and term human placenta.

@article{Bhattacharjee2010ExpressionAL,
  title={Expression and localization of ATP binding cassette transporter A1 (ABCA1) in first trimester and term human placenta.},
  author={Jhimli Bhattacharjee and Francesca Ietta and Emiliana Giacomello and Nicoletta Bechi and Roberta Romagnoli and Alessandra Fava and Luana Paulesu},
  journal={Placenta},
  year={2010},
  volume={31 5},
  pages={423-30}
}
ATP binding cassette transporter A1 (ABCA1) is a membrane transporter which performs cellular efflux of cholesterol and phospholipid. ABCA1's cholesterol transporting role in human placenta appears to be crucial for normal fetal development. Despite the critical importance of cholesterol in fetal development, expression of ABCA1 in the human placenta throughout gestation and its specific cellular localization have not been known yet. We therefore investigated ABCA1 expression in human placenta… CONTINUE READING