Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion

  title={Expression and importance of matrix metalloproteinase 2 and 9 (MMP-2 and -9) in human trophoblast invasion},
  author={Elsebeth Staun-Ram and Shlomit Goldman and Diana Gabarin and Eliezer Shalev},
  journal={Reproductive biology and endocrinology : RB&E},
  pages={59 - 59}
BACKGROUND The aim of this study was to examine the invasiveness of first trimester trophoblasts according to the secretion profile of MMP-2 and -9 at different gestational stages, and to test the similarity between primary trophoblast cell-culture and the JAR choriocarcinoma cell-line. METHODS First trimester trophoblasts were divided into two groups: 6-8 weeks (early) and 9-12 w (late) of gestation. The two trophoblast groups and JAR cells were cultured in medium, with various… CONTINUE READING
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Vascular endothelial growth factor , epidermal growth factor and fibroblast growth factor - 4 and - 10 stimulate trophoblast plasminogen activator system and metalloproteinase 9

  • U Puistola, L Ronnberg, H Martikainen, T Turpeenniemi-Hujanen
  • Mol Hum Reprod
  • 2004

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  • AM Bamberger, S Ezzat, +4 authors SL Asa
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