Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature.

Abstract

Expression of fibronectin (FN) isoforms containing CS1, a 25-amino acid sequence present within the alternatively spliced IIICS region of FN, has been analyzed in rheumatoid arthritis (RA) synovium. Unexpectedly, CS1-containing FN variants were exclusively found on endothelium but not extracellular matrix (ECM) of RA synovium. Lumenal expression of CS1 on… (More)

Topics

5 Figures and Tables

Slides referencing similar topics