Expression and functional activity of the IL-8 receptor type CXCR1 and CXCR2 on human mast cells.

Abstract

To further elucidate mechanisms involved in mast cell accumulation at sites of cutaneous inflammation, we have studied the ability of human leukemic mast cells (HMC-1 cells) to express functionally active IL-8 receptors. Expression of mRNA for both types of IL-8 receptors (CXCR1 and CXCR2) was demonstrated by PCR and of both proteins by flow cytometry… (More)

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Cite this paper

@article{Lippert1998ExpressionAF, title={Expression and functional activity of the IL-8 receptor type CXCR1 and CXCR2 on human mast cells.}, author={Undine Lippert and Metin Artuc and Andreas Gr{\"{u}tzkau and Annelie M{\"{o}ller and Anna Kenderessy-Szab{\'o} and Dirk Schadendorf and Johannes Norgauer and Karin Hartmann and Reinhard Schweitzer-Stenner and T Zuberbier and Beate Maria Henz and Sabine Kr{\"{u}ger-Krasagakes}, journal={Journal of immunology}, year={1998}, volume={161 5}, pages={2600-8} }