Expression and function of gastrin-releasing peptide (GRP) in normal and cancerous urological tissues.

@article{Ischia2014ExpressionAF,
  title={Expression and function of gastrin-releasing peptide (GRP) in normal and cancerous urological tissues.},
  author={Joseph J Ischia and Oneel Patel and Damien M Bolton and Arthur Shulkes and Graham S Baldwin},
  journal={BJU international},
  year={2014},
  volume={113 Suppl 2},
  pages={40-7}
}
Gastrin-releasing peptide (GRP) acts as an important regulatory peptide in several normal physiological processes and as a growth factor in certain cancers. In this review we provide a comprehensive overview of the current state of knowledge of GRP in urological tissues under both normal and cancerous conditions. GRP and its receptor, GRP-R, are expressed in the normal kidney and renal cancers. GRP can stimulate the growth of renal cancer cells. GRP and GRP-R are expressed in prostate cancer… CONTINUE READING

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