Expression and function of beta 2 integrins on alveolar macrophages from human and nonhuman primates.

@article{Albert1992ExpressionAF,
  title={Expression and function of beta 2 integrins on alveolar macrophages from human and nonhuman primates.},
  author={Richard K. Albert and Lisa J. Embree and J E McFeely and Dennis Durand Hickstein},
  journal={American journal of respiratory cell and molecular biology},
  year={1992},
  volume={7 2},
  pages={182-9}
}
The alveolar macrophage (AM) participates in diverse, adherence-related activities required for host defense and the inflammatory response. The beta 2 integrins (the CD11/CD18 heterodimer) mediate some of these activities on circulating leukocytes and peritoneal macrophages. We investigated expression of the CD11/CD18 leukocyte integrin subunits on AMs obtained by bronchoalveolar lavage of human and nonhuman primates. We also determined the role of the CD11/CD18 complex in AM chemotaxis and… CONTINUE READING

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