Expression and function of adrenomedullin and its receptors in Conn's adenoma cells.

@article{Forneris2001ExpressionAF,
  title={Expression and function of adrenomedullin and its receptors in Conn's adenoma cells.},
  author={Myriam Liliana Forneris and Lucia Gottardo and G. Albertin and Ludwick K Malendowicz and Gastone Giovanni Nussdorfer},
  journal={International journal of molecular medicine},
  year={2001},
  volume={8 6},
  pages={675-9}
}
Adrenomedullin (ADM) is a hypotensive peptide, that derives from the proteolytic cleavage of pro(p)ADM and acts through two subtypes of receptors, called L1-receptor (L1-R) and calcitonin receptor-like receptor (CRLR). CRLR may function as a calcitonin gene-related peptide or a selective ADM receptor depending on the expression of the subtype 1 or the subtypes 2 and 3 of a family of proteins, named receptor-activity modifying proteins (RAMPs). Reverse transcription (RT)-polymerase chain… CONTINUE READING

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