Expression and function of Cbl-b in T cells from patients with systemic lupus erythematosus, and detection of the 2126 A/G Cblb gene polymorphism in the Mexican mestizo population.

Abstract

Systemic lupus erythematosus (SLE) is characterized by abnormalities in the function of T and B lymphocytes and in the signaling pathways induced through their receptors. Cbl-b is an intracellular adaptor protein that plays a key role in the negative regulation of lymphocyte activity. We explored the expression and function of Cbl-b in T lymphocytes from… (More)
DOI: 10.1177/0961203310394896

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Cite this paper

@article{DonzPadilla2011ExpressionAF, title={Expression and function of Cbl-b in T cells from patients with systemic lupus erythematosus, and detection of the 2126 A/G Cblb gene polymorphism in the Mexican mestizo population.}, author={Lesly Don{\'i}z-Padilla and Ver{\'o}nica Del Carmen Mart{\'i}nez-Jim{\'e}nez and Perla C. Ni{\~n}o-Moreno and Carlos Abud-Mendoza and Berenice Hern{\'a}ndez-Castro and Roberto Gonz{\'a}lez-Amaro and Esther Layseca-Espinosa and Lourdes Baranda-C{\'a}ndido}, journal={Lupus}, year={2011}, volume={20 6}, pages={628-35} }