Expression and function of 5-HT4 receptors in the mouse enteric nervous system.

@article{Liu2005ExpressionAF,
  title={Expression and function of 5-HT4 receptors in the mouse enteric nervous system.},
  author={Min-tsai Liu and Matthew S. Geddis and Ying Wen and Wanda Setlik and Michael D. Gershon},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2005},
  volume={289 6},
  pages={
          G1148-63
        }
}
The aim of the current study was to identify enteric 5-HT(4) splice variants, locate enteric 5-HT(4) receptors, determine the relationship, if any, of the 5-HT(4) receptor to 5-HT(1P) activity, and to ascertain the function of 5-HT(4) receptors in enteric neurophysiology. 5-HT(4a), 5-HT(4b), 5-HT(4e), and 5-HT(4f) isoforms were found in mouse brain and gut. The ratio of 5-HT(4) expression to that of the neural marker, synaptophysin, was higher in gut than in brain but was similar in small and… Expand
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