Expression and distribution of vascular endothelial growth factor protein in human brain tumors

@article{Pietsch1997ExpressionAD,
  title={Expression and distribution of vascular endothelial growth factor protein in human brain tumors},
  author={Torsten Pietsch and Markus Maria Valter and Helmut K. Wolf and Andreas von Deimling and H.-J. Huang and Webster K Cavenee and Otmar Dieter Wiestler},
  journal={Acta Neuropathologica},
  year={1997},
  volume={93},
  pages={109-117}
}
Marked neovascularization is a hallmark of many neoplasms in the nervous system. Recent reports indicate that the endothelial mitogen vascular endothelial growth factor (VEGF) may play a critical role in the regulation of vascular endothelial proliferation in malignant gliomas. Using novel monoclonal antibodies to the VEGF polypeptide we have determined the expression and cellular distribution of VEGF protein in a representative series of 171 human central nervous system (CNS) tumors by… CONTINUE READING
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