Expression and distribution of tumor necrosis factor alpha in human lumbar intervertebral discs: a study in surgical specimen and autopsy controls.

@article{Weiler2005ExpressionAD,
  title={Expression and distribution of tumor necrosis factor alpha in human lumbar intervertebral discs: a study in surgical specimen and autopsy controls.},
  author={Christoph Weiler and Andreas Nerlich and Beatrice E Bachmeier and Norbert Boos},
  journal={Spine},
  year={2005},
  volume={30 1},
  pages={44-53; discussion 54}
}
STUDY DESIGN Immunohistochemical study of tumor necrosis factor alpha expression in autopsy and surgical specimens of human lumbar intervertebral discs. OBJECTIVES To investigate the occurrence and localization of tumor necrosis factor alpha in intervertebral disc tissue and to correlate its expression with age and the degree of disc degeneration. SUMMARY OF BACKGROUND DATA The source and origin of discogenic pain are as yet unknown. Recently identified changes of the cellular phenotype… CONTINUE READING
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