Expression and distribution of cyclooxygenase-2 in human periovulatory ovary.

@article{Tokuyama2001ExpressionAD,
  title={Expression and distribution of cyclooxygenase-2 in human periovulatory ovary.},
  author={Osamu Tokuyama and Yoshiro Nakamura and Ayako Muso and Ken-ichi Honda and Osamu Ishiko and Sachio Ogita},
  journal={International journal of molecular medicine},
  year={2001},
  volume={8 6},
  pages={603-6}
}
Cyclooxygenase, which converts arachidonic acid into prostaglandins, has two types of isoforms, cyclooxygenase-1 and cyclooxygenase-2 (COX-2). The latter is thought to be essential for the ovulatory mechanism. However, expression or distribution of COX-2 in periovulatory human ovary has not been reported. The aim of our study was to examine COX-2 expression and distribution in pre- and postovulatory human ovary. COX-2 was detected by Western blot analysis of pre-ovulatory human ovarian… CONTINUE READING