Expression and clinical significance of mammalian target of rapamycin/P70 ribosomal protein S6 kinase signaling pathway in human colorectal carcinoma tissue.

Abstract

The activation of mammalian target of rapamycin (mTOR) has been reported in tumor development, but the role of mTOR in colorectal carcinomas remains unclear. The aim of the present study was to investigate the significance of mTOR and its downstream effector 70 kDa ribosomal protein S6 kinase (P70S6K) in human colorectal carcinomas. The phosphorylated (p… (More)

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@article{Lu2015ExpressionAC, title={Expression and clinical significance of mammalian target of rapamycin/P70 ribosomal protein S6 kinase signaling pathway in human colorectal carcinoma tissue.}, author={Q Richard Lu and Jieshu Wang and Gang Yu and Tianhua Guo and Chunxiang Hu and Peng Ren}, journal={Oncology letters}, year={2015}, volume={10 1}, pages={277-282} }