Expression and characterization of the Escherichia coli fdo locus and a possible physiological role for aerobic formate dehydrogenase

@article{Abaibou1995ExpressionAC,
  title={Expression and characterization of the Escherichia coli fdo locus and a possible physiological role for aerobic formate dehydrogenase},
  author={Hafid Abaibou and Janine Pommier and S Benoit and Gérard Giordano and Marie-Andr{\~A}{\textcopyright}e Mandrand-Berthelot},
  journal={Journal of Bacteriology},
  year={1995},
  volume={177},
  pages={7141 - 7149}
}
In the presence of nitrate, the major anaerobic respiratory pathway includes formate dehydrogenase (FDH-N) and nitrate reductase (NAR-A), which catalyze formate oxidation coupled to nitrate reduction. Two aerobically expressed isoenzymes, FDH-Z and NAR-Z, have been recently characterized. Enzymatic analysis of plasmid subclones carrying min 88 of the Escherichia coli chromosome was consistent with the location of the fdo locus encoding FDH-Z between the fdhD and fdhE genes which are necessary… 
Biosynthesis of the respiratory formate dehydrogenases from Escherichia coli: characterization of the FdhE protein
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TLDR
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A-Type Carrier Protein ErpA Is Essential for Formation of an Active Formate-Nitrate Respiratory Pathway in Escherichia coli K-12
TLDR
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Model-assisted formate dehydrogenase-O (fdoH) gene knockout for enhanced succinate production in Escherichia coli from glucose and glycerol carbon sources
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References

SHOWING 1-10 OF 59 REFERENCES
Structural genes for nitrate-inducible formate dehydrogenase in Escherichia coli K-12.
TLDR
It is concluded that regulation of fdnGHI and narGHJI expression is mediated through common pathways.
Identification and expression of the Escherichia coli fdhD and fdhE genes, which are involved in the formation of respiratory formate dehydrogenase
TLDR
Initial experiments indicate that the region between the two genes seems not to be essential to FDH-PMS activity, which might suggest the participation of fdhE in the synthesis of the selenopolypeptide of FDH -PMS.
Genetic evidence that genes fdhD and fdhE do not control synthesis of formate dehydrogenase-N in Escherichia coli K-12
TLDR
These complementation tests indicate that the S. typhimurium fdnC and fdnB genes are functionally homologous to the E. coli fdhD and fdhE genes, respectively, indicating that the rha-linked Salmonella typhIMurium genes are required primarily for formate dehydrogenase-N activity.
Identification of the formate dehydrogenases and genetic determinants of formate-dependent nitrite reduction by Escherichia coli K12.
TLDR
It is concluded that all three of the known formate dehydrogenases of E. coli can contribute to the transfer of electrons from formate to the Nrf pathway.
The identification of mutants of Escherichia coli deficient in formate dehydrogenase and nitrate reductase activities using dye indicator plates
TLDR
A detailed analysis of the molecular genetics of the Escherichia coli system is begun with particular emphasis on firstly the unambiguous characterizations of the products of the various structural genes so far described, and secondly the identification of the regulatory genes responsible for the control of structural gene expression.
A second phenazine methosulphate-linked formate dehydrogenase isoenzyme in Escherichia coli.
Mutants of Escherichia coli specifically deficient in respiratory formate dehydrogenase activity.
TLDR
Construction of merodiploid strains harbouring various combinations of the mutated alleles, fdhE on the episome and fdhD on the chromosome, led to the restoration of FDH-PMS activity by complementation of the products encoded by the respective wild-type alleles.
Expression and operon structure of the sel genes of Escherichia coli and identification of a third selenium-containing formate dehydrogenase isoenzyme
TLDR
A detailed analysis of the expression of the sel genes showed that transcription was constitutive, being influenced neither by aerobiosis or anaerobiosis nor by the intracellular selenium concentration, and it is probable that this selenopolypeptide constitutes a major component of the formate oxidase.
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