Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori.

@article{Ge2006ExpressionAC,
  title={Expression and characterization of a histidine-rich protein, Hpn: potential for Ni2+ storage in Helicobacter pylori.},
  author={Ruiguang Ge and Rory M Watt and Xuesong Sun and Julian Alexander Tanner and Qing-Yu He and Jinliang Huang and Hongzhe Sun},
  journal={The Biochemical journal},
  year={2006},
  volume={393 Pt 1},
  pages={
          285-93
        }
}
Hpn is a small cytoplasmic protein found in Helicobacter pylori, which binds Ni2+ ions with moderate affinity. Consisting of 60 amino acids, the protein is rich in histidine (28 residues, 46.7%), as well as glutamate, glycine and serine residues (in total 31.7%), and contains short repeating motifs. In the present study, we report the detailed biophysical characterization of the multimeric status and Ni2+-binding properties of purified recombinant Hpn under physiologically relevant conditions… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 32 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

Similar Papers

Loading similar papers…