Expression and cellular localization of metalloproteases ADAMs in high graded carotid artery lesions.

@article{Pelisek2012ExpressionAC,
  title={Expression and cellular localization of metalloproteases ADAMs in high graded carotid artery lesions.},
  author={Jaroslav Pelisek and Julia Pongratz and L. S. Deutsch and Christian Reeps and Thomas Stadlbauer and Hans-Henning Eckstein},
  journal={Scandinavian journal of clinical and laboratory investigation},
  year={2012},
  volume={72 8},
  pages={
          648-56
        }
}
  • Jaroslav Pelisek, Julia Pongratz, +3 authors Hans-Henning Eckstein
  • Published in
    Scandinavian journal of…
    2012
  • Medicine
  • Metalloproteases with a disintegrin domain (ADAM) has already been implicated in various cellular processes such as cytokine and growth factor shedding, proliferation, migration, and degradation of extracellular matrix. Their role in the development and progression of atherosclerosis in carotid lesions is however unknown. The aim of the study was to analyze expression of proteolytic ADAMs (8, 9, 10, 12, 15, 17) and their inhibitors TIMP-1, -3 in patients with high-graded carotid artery stenosis… CONTINUE READING

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