Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury.

@article{Wang2012ExpressionAC,
  title={Expression and cell distribution of metabotropic glutamate receptor 5 in the rat cortex following traumatic brain injury.},
  author={Jia-Wei Wang and Han-dong Wang and Wu-Zhao Zhong and Ning Li and Z Cong},
  journal={Brain research},
  year={2012},
  volume={1464},
  pages={73-81}
}
Traumatic brain injury (TBI)-released excessive glutamate resulted in the activation of glutamate receptors including the metabotropic glutamate receptor 5 (mGluR5). To investigate the expression and cell distribution of mGluR5 in the rat cortex following TBI, western blot and quantitative real-time PCR were used to study the protein and mRNA level of mGluR5 respectively while immunohistochemistry analysis and double immunofluorescence with neural cell marker were used to define the cell… CONTINUE READING
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