Expression and Significance of Beclin-1 and Bcl-2 in Gastric Cancer

  title={Expression and Significance of Beclin-1 and Bcl-2 in Gastric Cancer},
  author={Meisui Lin and Wen-dan Yuan and Xiaohui Sun and Zhiqiang Qin},
  journal={International journal of sciences},
Objective To investigate the role and correlation of Beclin-1 and Bcl-2 in the occurrence and progression of gastric cancer. Methods The expression of Beclin-1 and Bcl-2 in 78 cases of gastric cancer, 30 cases of atypical hyperplasia and 20 cases of chronic non-atrophic gastritis was examined by immunohistochemical staining. Results The positive rate of Beclin-1 in gastric cancer was significantly lower than those in atypical hyperplasia and chronic non-atrophic gastritis(χ2=9.298,7.437, P 0.05… Expand
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