Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy

@inproceedings{Sadikovi2009ExpressionAO,
  title={Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy},
  author={Bekim Sadikovi{\'c} and Paul Scott Thorner and Susan Chilton-Macneill and Jeff W. Martin and Nilva de Karla Cervigne and Jeremy A Squire and Maria Zielenska},
  booktitle={BMC Cancer},
  year={2009}
}
Human osteosarcoma is the most common pediatric bone tumor. There is limited understanding of the molecular mechanisms underlying osteosarcoma oncogenesis, and a lack of good diagnostic as well as prognostic clinical markers for this disease. Recent discoveries have highlighted a potential role of a number of genes including: RECQL4, DOCK5, SPP1, RUNX2, RB1, CDKN1A, P53, IBSP, LSAMP, MYC, TNFRSF1B, BMP2, HISTH2BE, FOS, CCNB1, and CDC5L. Our objective was to assess relative expression levels of… CONTINUE READING
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RUNX 1 and RUNX 2 upregulate Galectin3 expression in human pituitary tumors

  • HY Zhang, L Jin, +5 authors RV Lloyd
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