Expression Profile of microRNAs and Their Targeted Pathways in Human Ovaries Detected by Next-Generation Small RNA Sequencing.

@article{Xu2016ExpressionPO,
  title={Expression Profile of microRNAs and Their Targeted Pathways in Human Ovaries Detected by Next-Generation Small RNA Sequencing.},
  author={Bo Xu and Yuan-wei Zhang and Sheng-Xia Zheng and Xian-hong Tong and Yu-sheng Liu},
  journal={DNA and cell biology},
  year={2016},
  volume={35 5},
  pages={226-34}
}
Recently, post-transcriptional gene regulation by microRNAs (miRNAs) has been reported to play a key role during ovary development and differentiation. However, there are no published studies identifying miRNA profiles of human ovarian tissues directly using next-generation sequencing technology. In the human ovary, a total of 762 known and 21 novel human miRNAs were detected, indicating that human ovaries have a complex population of small RNAs. To confirm the miRNA profile in human ovaries… CONTINUE READING
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