Expression Profile of microRNAs Regulating Proliferation and Differentiation in Mouse Adult Cardiac Stem Cells

@inproceedings{BrsRosrio2013ExpressionPO,
  title={Expression Profile of microRNAs Regulating Proliferation and Differentiation in Mouse Adult Cardiac Stem Cells},
  author={Luis Br{\'a}s-Ros{\'a}rio and Alex Matsuda and Ana Isabel Pinheiro and Rui Gardner and Telma A Lopes and Andreia J. Amaral and Margarida Gama-Carvalho},
  booktitle={PloS one},
  year={2013}
}
The identification of cardiac cells with stem cell properties changed the paradigm of the heart as a post mitotic organ. These cells proliferate and differentiate into cardiomyocytes, endothelial and vascular smooth muscle cells, providing for cardiac cell homeostasis and regeneration. microRNAs are master switches controlling proliferation and differentiation, in particular regulating stem cell biology and cardiac development. Modulation of microRNAs -regulated gene expression networks holds… CONTINUE READING
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